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Table 2 Levels of IgG antibodies against P. vivax blood stage proteins according to the studied genotypes

From: Cytokine gene polymorphisms are not associated with anti-PvDBP, anti-PvAMA-1 or anti-PvMSP-119 IgG antibody levels in a malaria-endemic area of the Brazilian Amazon

Gene SNP PvAMA-1 (n = 135) P value PvDBP (n = 135) P value PvMSP-119
(n = 128)
P value
INFG +874T > A   0.19   0.40   0.42
  AA 1.36 (0.63–2.78)   1.58 (0.78–7.29)   2.92 (1.00–7.63)  
  AT 1.14 (0.51–2.18)   1.41 (0.77–4.73)   2.05 (0.49–6.64)  
  TT 2.50 (1.18–3.00)   5.17 (0.86–18.5)   4.66 (1.50–8.11)  
TNFA 1031T > C   0.74   0.42   0.71
  TT 1.41 (0.60–2.97)   1.34 (0.79–5.38)   3.74 (0.96–7.57)  
  TC 1.49 (0.58–2.50)   1.66 (0.79–6.87)   2.60 (0.51–6.93)  
  CC 1.45 (1.01–1.52)   8.57 (0.73–14.89)   2.12 (1.32–2.59)  
TNFA 308G > A   0.41   0.58   0.50
  GG 1.67 (0.65–2.80)   1.66 (0.79–6.30)   2.92 (0.89–7.58)  
  GA 1.14 (0.58–2.23)   1.48 (0.73–3.42)   2.61 (1.18–6.54)  
  AA 0.62 (0.51–0.62)   1.39 (0.96–1.39)   1.30 (0.28–1.30)  
TNFA 238G > A   0.76   0.97   0.61
  GG 1.45 (0.64–2.66)   1.59 (0.81–5.59)   2.61 (0.94–7.47)  
  GA 1.34 (0.53–2.91)   1.48 (0.76–7.16)   5.15 (1.69–8.16)  
  AA 2.32 (2.32–2.32)   1.28 (1.28–1.28)   3.04 (3.04–3.04)  
IL10 819C > T   0.79   0.57   0.99
  CC 1.35 (0.63-2.53)   2.01 (0.79–5.91)   3.50 (0.55–7.48)  
  CT 1.45 (0.60-2.77)   1.29 (0.77–5.06)   2.61 (0.87–7.60)  
  TT 2.22 (0.83–2.84)   2.18 (1.35–6.31)   1.98 (1.22–7.13)  
IL10 592C > A   0.86   0.86   0.77
  CC 1.41 (0.62–2.50)   1.59 (0.76–5.91)   4.92 (1.10–7.63)  
  CA 1.52 (0.62–2.78)   1.46 (0.81–5.46)   2.59 (0.94–7.26)  
  AA 1.22 (0.52–2.85)   1.84 (1.21–4.32)   2.50 (1.07–5.97)  
  1. Values are presented as medians (IQ)