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Table 3 Effects of prenatal exposure to Plasmodium falciparum, gravidity, Infant birth weight, age of the mother at delivery, and season of birth to clinical malaria episodes: binary logistic regression

From: Prenatal exposure to Plasmodium falciparum increases frequency and shortens time from birth to first clinical malaria episodes during the first two years of life: prospective birth cohort study

Factors

BLR-univariate analysis

BLR-multivariate analysis

OR (CI 95 %)

p value

AOR (CI 95 %)

p value

In utero exposure to Plasmodium falciparum

Non-exposure to P. falciparum in utero

1 (–)

–

1 (–)

–

Exposure to P. falciparum in utero

4.632 (2.248–9.541)

p < 0.01

4.791 (2.21–10.38)

p < 0.01

Gravidity of mothers

Primigravidity

1 (–)

–

1 (–)

–

Multigravidity

0.752 (0.4–1.415)

0.372

0.973 (0.475–1.990)

0.939

Infant birth weight

Normal birth weight

1 (–)

–

1 (–)

–

Low birth weight

0.441 (0.189–1.031)

0.059

0.556 (0.209–1.477)

0.239

Age of mothers (years)

40–50

1

–

1 (–)

–

<18

1.833 (0.626–5367)

0.269

2.120 (0.672–6.687)

0.20

18–28

1.100 (0.329–3.677)

0.877

1.196 (0.328–4.361)

0.786

29–39

1.615 (0.779–3.351)

0.198

2.013 (0.913–4.438)

0.083

Infant season of birth

Dry season

1.0

–

1 (–)

–

Wet season

0.736 (0.311–1.741)

0.485

0.917(0.338–1.2.484)

0.864

  1. Prenatal exposure to Plasmodium falciparum significantly associated with clinical malaria episodes in univariate and Multivariate analysis (p < 0.01)
  2. OR Odds Ratio, AOR Adjusted Odds Ratio, CI Confidence interval, BLR Binary logistic regression