Fig. 5
From: A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents
Minimal concentration for cidal effect of TCMDC-125114 with the Pf77 coding gene. With drug exposure for 48 h, increasing concentrations were tested of: a chloroquine (negative control); or b TCMDC-125114 (active against gametocytes). TCMDC-125114 was used at 20 × IC50 during all the experiments; TCMDC-125114 20 × IC50 with drug exposure throughout the 144 h of the experiment (T∞) was used as a positive control