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Table 1 Study subjects demographics

From: Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity

 

True-immunized

Mock-immunized

Infectivity controls

1999–2000

2001–2002

Gender

 Male

5

12

11

4

 Female

0

0

2

1

Total

5

12

13

5

Age (mean + SD)

42 ± 10

34 ± 8

34 ± 7

36 ± 8

Race/ethnicity

 African–American

0

3

1

2

 Caucasian

5

8

7

2

 Hispanic

0

0

0

0

 Not known

0

1

5

1

Total: true-immunized

 

17

  

Total: mock-immunized

 

13

Total: infectivity controls

 

5

  1. Seventeen subjects were enrolled into the true-immunized group that received bites of PfRAS mosquitoes; five subjects were enrolled in 1999–2000 and 12 subjects were enrolled in 2001–2002. Thirteen subjects were enrolled into the mock-immunized group that received bites of uninfected mosquitoes, and six subjects enrolled as infectivity controls of whom five received CHMI
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Malaria Journal

ISSN: 1475-2875

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