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Table 3 Pfmdr1 and Pfcrt allelic types in parental and resistant P. falciparum lines

From: In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin

Parasite line

Pfmdr1 Amino acid position

Pfcrt Amino acid positions

86

184

185

72

73

74

75

76

W2

Y

Y

I

C

V

I

E

T

W2 c3B

Y

Y

K

C

V

I

E

T

W2 c5A

Y

Y

K

C

V

I

E

T

W2 c5B

Y

Y

K

C

V

I

E

T

D6

N

Y

I

C

V

M

N

K

D6 c3A

N

Y

K

C

V

M

N

K

D6 c3B

N

Y

K

C

V

M

N

K

D6 c5A

N

Y

K

C

V

M

N

K

D6 c5B

N

Y

K

C

V

M

N

K

  1. D6 c3A, D6 c3B, D6 c5A, D6 c5B = D6 P. falciparum line exposed to artemisinin. W2 c3B, W2 c5A, W2 c5B = W2 P. falciparum line exposed to artemisinin
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Malaria Journal

ISSN: 1475-2875

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