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Table 3 Distribution of different pvdhfr and pvdhps combination haplotype Kolkata and Purulia

From: Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India

Genotype Isolates in KMC Isolates in P PVDHFR PVDHPS Allele type
15 33 50 57 58 61 64 117 173 373 380 382 383 384 512 553 585 601
G1 11 17 A P N F S T V S I S E S A P K A V M Wild
G2 3 1 A P N F R T V S I S E S A P K A V M SM
G3 6 6 A P N F R T V N I S E S A P K A V M DM
G4 0 4 A P N F S T V N I S E S A P K A V M SM
G5 8 3 A P N F S T V S I S E S G P K A V M SM
G6 15 7 A P N F R T V N I S E S G P K A V M TM
G7 7 0 A P N F R T V N I S E S G P K G V M QM
G8 0 6 A P N F R T V S I S E S A P K G V M DM
G9 0 3 A P N F S T V S I S E S A L K A V M SM
G10 2 0 A P N L R T V N I S E S G P K G V M QTM
  1. Bold amino acids are the mutant codon
  2. SM, DM, TM, QM and QTM are respectively denote as single mutant, double mutant, triple mutant, quadruple mutant and quintuple mutant allele