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Fig. 4 | Malaria Journal

Fig. 4

From: Integrin αDβ2 (CD11d/CD18) mediates experimental malaria-associated acute respiratory distress syndrome (MA-ARDS)

Fig. 4

F4/80-positive leukocytes accumulate in the alveoli in Plasmodium berghei ANKA-induced experimental MA-ARDS and are reduced in αDβ2-deficient mice. Lung tissue from α +/+D and α −/−D mice infected with P. berghei was harvested at 7 days after infection. Lung slices were incubated with anti-F4/80 as the primary antibody and HRP-conjugated secondary antibody. The sections were examined and photographed using an Olympus BX41 microscope at ×200 magnification (scale bars 200 mm). a Sections from a control α +/+D mouse. b Section from a control α −/−D mouse. c Lung tissue from an infected α +/+D wild type animal. d Section from an infected α −/−D mouse. The staining patterns shown in ad are representative of those in lung tissue from 3 individual mice for each condition

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