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Table 1 Properties of the antibodies used in the study

From: Phagocytosis-inducing antibodies to Plasmodium falciparum upon immunization with a recombinant PfEMP1 NTS-DBL1α domain

  Antibody type ELISA-reactivity (ITvar60 NTS-DBL1α) Surface reactivity (FCR3S1.2) Rosette disruption (FCR3S1.2) Opsonization for phagocytosis (FCR3S1.2)
mAbV2–3 (IgG2b)a IgG2b + + +
mAbV2–6 (IgG2b)a IgG2b + + +
mAbV2–14.1 (IgG2b)a IgG2b + + +
mAbV2–14.2 (IgG2b)a IgG2b + + +
mAbV2–4 (IgG2a)a IgG2a + + +
mAbV2–7 (IgG2a)a IgG2a + + + +
mAbV2–13 (IgG2a)a IgG2a + + + +
mAbV2–16 (IgG2a)a IgG2a + + +
mAbV2–17.1 (IgG2a)a IgG2a + + + +
mAbSly Da IgG2b
ITvar60 goat IgGa IgG + + +
Control goat IgGa IgG
IM1 Serum + + +
IM2 Serum + + +
IM3 Serum + + +
IM4 Serum + + +
IM5 Serum + + +
IM6 Serum + + + +
IMP Serum + + +
SCP Serum
  1. Table summarizes the sample name (mAb monoclonal antibody, IM immune malaria, IMP immune malaria pool, SCP Swedish control pool) and antibody type with their corresponding activity (±) in different assays. Positivity was determined based on the cut-off criteria specified in the “Methods” section
  2. aELISA reactivity, surface reactivity and rosette disruption activity for these antibodies have been published elsewhere [25] and are accordingly reported here