Skip to main content


Fig. 5 | Malaria Journal

Fig. 5

From: Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence

Fig. 5

Exposure to Esp_Z limits Plasmodium’s antioxidant response. Relative P. berghei pre-ookinete expression of thioredoxin reductase (trxr), thioredoxin (trx), thioredoxin 1 (trx1), peroxiredoxin-1 (tpx-1), and 1-Cys peroxiredoxin (1-cys-prx) upon in vitro co-culture with Esp_Z (blue) or Pseudomonas putida (Ppu, black). RT-qPCR datasets were normalized to the level of expression of 18SrRNA, a PBS control, and the expression at 1 h post-exposure for each experimental group. Bars represent the mean ± the standard error of the mean of six biological replicates over two independent experiments (3 + 3). Significance was determined using a two-tailed one sample t-test to determine whether each transcript was significantly up- or down-regulated (*p < 0.05; **p < 0.01; ***p < 0.001)

Back to article page