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Table 3 Molecular markers and haplotype prevalence

From: Malaria in urban, semi-urban and rural areas of southern of Gabon: comparison of the Pfmdr 1 and Pfcrt genotypes from symptomatic children

Prevalence by sites [%; (n/N)]

Genes

Codons

Genotypes

LTV

FGM

KMT

FCV

p

Pfcrt

 SNPs

76

K

16.5 (33/200)

27.8 (10/36)

17.4 (20/115)

29.4 (15/51)

0.09

K/T

10.5 (21/200)

0.0 (0/36)

0.0 (0/115)

17.6 (9/51)

ND

86

N

57.8 (144/249)

51.2 (21/41)

45.4 (49/108)

62.2 (23/37)

0.12

N/Y

10.4 (26/249)

17.1 (7/41)

17.6 (19/108)

5.4 (2/37)

0.10

184

Y/F

0.0

0.0

0.0

0.0

ND

F

73.8 (175/237)

81.6 (31/38)

83.2 (84/101)

80.6 (25/31)

0.24

1246

D

94.1 (255/271)

100.0 (32/32)

85.6 (95/111)

87.3 (48/55)

ND

D/Y

3.3 (9/271)

0.0 (0/32)

12.6 (14/111)

9.1 (5/55)

ND

pfmdr1

 Haplotypes

86/184/1246

NFD

46.6 (110/236)

45.5 (15/33)

35.0 (31/89)

40.0 (10/25)

0.28

NYD

14.0 (33/236)

9.1 (3/33)

6.7 (6/89)

16.0 (4/25)

ND

YFD

25.8 (61/236)

42.4 (14/33)

40.4 (36/89)

32.0 (8/25)

0.03

YYD

8.5 (20/236)

3.0 (1/33)

4.5 (4/89)

4.0 (1/25)

ND

NFY

1.3 (3/236)

0.0

6.7 (6/89)

0.0

ND

NYY

0.0

0.0

4.5 (4/89)

4.0 (1/25)

ND

YYY

1.7 (4/236)

0.0

2.2 (2/89)

0.0

ND

YFY

2.1 (5/236)

0.0

0.0

4.0 (1/25)

ND

  1. ND p undetermined; LTV Lastourville; FGM Fougamou; KMT Koula-Moutou; FCV Franceville