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Table 1 Clinical parameters of uncomplicated and severe malaria patients from day-0 to day-7

From: Plasma levels of Galectin-9 reflect disease severity in malaria infection

Clinical parametersa

Day 0

Day 7

UM

SM

UM

SM

Haemoglobin (g/dL)

11.9 (6–14.4)

11 (6.3–14)b ns

10.3 (6.3–14.2)

8.6 (6.3–9.7)c, **

Direct Bilirubin (mg/dL)

0.29 (0.06–2.6)

0.98 (0.3–5.7)b, ***

0.12 (0.06–0.55)

0.235 (0.1–0.64)c, *

Platelets (cell/μL)

85.5 (16–502)

27 (16–59)b, **

249.5 (138–563)

226 (130–429)c ns

Creatinine (mg/dL)

1 (0.6–1.6)

1.25 (1–6.4)b, **

0.8 (0.5–1.3)

0.775 (0.6–1.15)c ns

BUN (mg/dL)

19.5 (6–56.7)

44.5 (20.3–154.4)b, ****

8.5 (4.5–16.5)

9 (5–12)c ns

AST (U/L)

35 (18–230)

80 (40–295)b, **

34.00 (12.00–97)

43.50 (20–295)c ns

Sodium (mmol/L)

135 (118–147)

129.5 (118–144)b, *

140 (136–146)

138 (134–144)c ns

Bicarbonate (mmol/L)

22 (15–23)

20 (17–25)b, *

22 (20–26)

21 (21–24)c ns

  1. Mann–Whitney non-parametric test was used to assess differences between parameters
  2. UM uncomplicated malaria; SM severe malaria
  3. **** P < 0.0001, *** P < 0.001, ** P < 0.01, and * P < 0.05
  4. aMedian and range
  5. bCompared UM to SM on day 0
  6. cUM to SM 7