Fig. 2

Plasmodium cynomolgi B strain infection in rhesus macaques induces moderate to severe anaemia. a Haemoglobin concentrations of five rhesus macaques are shown prior to infection, during the acute primary, and after the peak of parasitaemia. b Haemoglobin kinetics in relation to parasitaemia and the relationship between haemoglobin and MCV (c) for up to 100 days after inoculation are shown. Orange bars in Panel B indicate when peripheral blood and bone marrow aspirates were collected for retrospective systems biology analysis. Statistical analysis was performed by a Friedman’s Test with Dunn’s multiple comparison post-hoc for Panel a; ^*p < 0.05, ns not significant