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Table 4 GOTERM categories recorded significantly enriched compare to the reference set (total number of transcripts detected by microarray), terms with a lowest count limit of 2 and an ease score p value <0.05

From: Investigation of mechanisms of bendiocarb resistance in Anopheles gambiae populations from the city of Yaoundé, Cameroon

Category Go-term functions FE p value Benjaminia
Overexpressed in resistant vs control
GOTERM_MF_FAT Peptidase activity acting on L-amino acid peptides 21 0.009 0.21
GOTERM_MF_FAT Peptidase activity 21 0.011 0.13
GOTERM_MF_FAT Proteolysis 21 0.024 0.36
Overexpressed in control vs Kisumu
GOTERM_MF_FAT Electron carrier activity 5 0.001 0.17
SMART PhBP 1.7 0.0048 0.25
GOTERM_BP_FAT Oxidation reduction 5.9 0.0062 0.93
SP_PIR_KEYWORDS Oxidoreductase 4.2 0.0081 0.46
INTERPRO Cytochrome P450 2.9 0.0092 0.95
SP_PIR_KEYWORDS Monooxygenase 2.5 0.012 0.36
INTERPRO Odorant binding protein PhBP 1.7 0.012 0.85
INTERPRO Pheromone/general odorant binding protein, PBP/GOBP 2.1 0.013 0.76
INTERPRO Cytochrome P450, conserved site 2.5 0.019 0.79
Overexpressed in resistant vs Kisumu
GOTERM_MF_FAT electron carrier activity 7 0.00015 0.02
SP_PIR_KEYWORDS Iron 5.1 0.00072 0.049
INTERPRO Cytochrome P450 4.5 0.0011 0.22
GOTERM_MF_FAT Iron ion binding 6.4 0.0017 0.11
SP_PIR_KEYWORDS Monooxygenase 3.8 0.0021 0.072
SP_PIR_KEYWORDS Oxidoreductase 5.7 0.0022 0.051
GOTERM_BP_FAT Oxidation reduction 7.6 0.003 0.58
INTERPRO Cytochrome P450 3.8 0.0033 0.3
COG_ONTOLOGY Posttranslational modification, protein turnover, chaperones 4.5 0.005 0.044
SP_PIR_KEYWORDS Haem 3.8 0.0058 0.097
GOTERM_MF_FAT Tetrapyrrole binding 4.5 0.0098 0.36
GOTERM_MF_FAT Haem binding 4.5 0.0098 0.36
  1. FE fold enrichment
  2. aBenjamini and Hochberg multiple testing correction