Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone

Malaria Journal

Table 3 Relative percent change in malaria indicators and Ebola alerts in the health facilities in MDA (n = 34 PHUs) and non-MDA chiefdoms (n = 14 PHUs) during post-MDA weeks using interrupted time-series regression

Chiefdoms	Indicators	Relative percent changes in 1st MDA round (%)					Relative percent changes in 2nd MDA round (%)
		Weeks post 1st MDA					Week number after second MDA
		Baseline	1	2	3	4	1	2	3	4
MDA Chiefdoms	Malaria (clinical + confirmed)	603	−45^*	−43^*	−42^*	−10	−36^*	−20	−3	25
	RDT tested	516	−43^*	−41^*	−36^*	−6	−39^*	−16	−31^*	23
	RDT positive	398	−47^*	−62^*	−53^*	−35^*	−55^*	−49^*	−58^*	−26^*
	Test positivity rate	77	−6^*	−35^*	−25^*	−29^*	−22^*	−35^*	−34^*	−34^*
	Proportion of outpatient malaria (of all-cause outpatient)	28	−33^*	−57^*	−44^*	−33^*	−52^*	−60^*	−67^*	−46^*
	Non-malaria	1019	−9	11	2	14	24	77	84	86
	Ebola alerts	324	−30^*	−12	−23^*	−18	−48^*	−59^*	−58^*	−60^*
	Inpatient malaria cases	78	−31^*	−20^*	−9	8	−19	−26	−25	−0.6
	Proportion of inpatient malaria (of all-cause inpatients)	35	−24^*	−16^*	16	24	−2	−70	−16	28
Non-MDA Chiefdoms	Malaria (clinical + confirmed)	290	−9^*	−2	−33^*	−26^*	−33^*	−18^*	−33^*	−39^*
	RDT tested	403	−23^*	−11^*	−50^*	−44^*	−43^*	−44^*	−36^*	−51^*
	RDT positive	237	−30^*	−9	−47^*	−37^*	−53^*	−38^*	−45^*	−51^*
	Test positivity rate	59	−8^*	4	8	16^*	−14^*	17	−7	6
	Proportion of outpatient malaria (of all-cause outpatients)	39	−33^*	−2	−22^*	−3	−37^*	−20^*	−31^*	−27^*
	Non-malaria	374	29^*	−8	−20^*	−35	−4	−14	−2	−21
	Ebola alerts	198	0.1	2	7^*	10^*	−16^*	−19^*	−22^*	−32^*

Percentages with asterisk are significant changes (95 % CI that excluded zero). Negative changes are decrease and positive changes are increase in trends post-MDA compared to trends of pre-MDA weeks

ISSN: 1475-2875