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Table 3 Relative percent change in malaria indicators and Ebola alerts in the health facilities in MDA (n = 34 PHUs) and non-MDA chiefdoms (n = 14 PHUs) during post-MDA weeks using interrupted time-series regression

From: Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone

Chiefdoms Indicators Relative percent changes in 1st MDA round (%) Relative percent changes in 2nd MDA round (%)
Weeks post 1st MDA Week number after second MDA
Baseline 1 2 3 4 1 2 3 4
MDA Chiefdoms Malaria (clinical + confirmed) 603 −45* −43* −42* −10 −36* −20 −3 25
RDT tested 516 −43* −41* −36* −6 −39* −16 −31* 23
RDT positive 398 −47* −62* −53* −35* −55* −49* −58* −26*
Test positivity rate 77 −6* −35* −25* −29* −22* −35* −34* −34*
Proportion of outpatient malaria (of all-cause outpatient) 28 −33* −57* −44* −33* −52* −60* −67* −46*
Non-malaria 1019 −9 11 2 14 24 77 84 86
Ebola alerts 324 −30* −12 −23* −18 −48* −59* −58* −60*
Inpatient malaria cases 78 −31* −20* −9 8 −19 −26 −25 −0.6
Proportion of inpatient malaria (of all-cause inpatients) 35 −24* −16* 16 24 −2 −70 −16 28
Non-MDA Chiefdoms Malaria (clinical + confirmed) 290 −9* −2 −33* −26* −33* −18* −33* −39*
RDT tested 403 −23* −11* −50* −44* −43* −44* −36* −51*
RDT positive 237 −30* −9 −47* −37* −53* −38* −45* −51*
Test positivity rate 59 −8* 4 8 16* −14* 17 −7 6
Proportion of outpatient malaria (of all-cause outpatients) 39 −33* −2 −22* −3 −37* −20* −31* −27*
Non-malaria 374 29* −8 −20* −35 −4 −14 −2 −21
Ebola alerts 198 0.1 2 7* 10* −16* −19* −22* −32*
  1. Percentages with asterisk are significant changes (95 % CI that excluded zero). Negative changes are decrease and positive changes are increase in trends post-MDA compared to trends of pre-MDA weeks