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Table 1 Demographic and haematological parameters of the study population

From: Immune response pattern in recurrent Plasmodium vivax malaria

 

Endemic control (n = 20)

Primary malaria (n = 36)

Recurrent malaria (n = 19)

p value*

Age (years), mean (SD)

27.1 (7.4)

35.4 (14.3)

39.5 (12.0)

0.005

Man/woman (%)

45/55

64/36

85/15

Malaria episodesa

3.0 (1.5–4.0)

Last malaria attackb

4.0 (3.0–6.0)

Haematological parametersc

    

 RBC × 103/mm3

4.8 (4.5–5.4)

4.7 (4.2–5.3)

5.0 (4.4–5.2)

0.839

 Haemoglobin (g/dL)

13.2 (12.5–14.1)

13.4 (11.5–14.4)

13.1 (12.2–14.1)

0.592

 Haematocrit (%)

43.9 (40.5–46.8)

41.9 (36.5–45.7)

42.0 (39–46.5)

0.461

 Platelets × 103/mm3

289.0 (212.5–325.2)

69.0 (37.8–100.5)d

112.0 (53–120)d

< 0.001

 WBC × 103/mm3

6.7 (6.1–7.8)

5.7 (4.0–7.3)

5.6 (4.7–6.8)

0.018

 Lymphocytes × 103/mm3

2.0 (1.6–2.6)

1.3 (0.7–1.8)d

1.0 (0.5–1.3)d

< 0.001

 Monocytes × 103/mm3

0.7 (0.5–0.8)

0.3 (0.2–0.5)d

0.5 (0.3–0.9)

0.014

 Neutrophils × 103/mm3

3.8 (3.5–5.1)

3.3 (2.1–5.1)

4.0 (3.0–4.7)

0.436

  1. Patients were grouped according to their malaria diagnosis based on microscopy data
  2. aThe patients were tested at one time point and recurrent malaria episodes recorded
  3. bTime in months
  4. cData expressed as median and interquartile range (IQR25–IQR75)
  5. dSignificant differences as compared to endemic controls
  6. * Kruskal–Wallis analyses followed by Dunn’s post-test