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Fig. 2 | Malaria Journal

Fig. 2

From: An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

Fig. 2

SMFA comparison with 4B7 mAb. In LMVR, mouse 4B7 mAb was tested at 6 (n = 9), 23 (n = 35) and 94 (n = 181) μg/mL in multiple feeding experiments. At TropIQ, 4B7 mAb was tested at the same concentrations in two independent feeding assays. Individual feeding data and the best estimate of %TRA (with the 95 % CIs) from multiple feeds (LMVR-Comb or TropIQ-Comb) are shown. Average oocysts in a negative control antibody (normal mouse IgG) of TropIQ-feed 1(F1) and -feed 2(F2) experiments were 6.5 and 4.2, respectively. Average oocysts in negative control antibodies for LMVR experiments was 21.6 (SD = 18.5)

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