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Table 3 The frequencies of IFN- γ -secreting cells following in vitro stimulation of PBMC

From: Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

 

% IFN-γ secreting CD4+ T cells

% IFN-γ secreting CD8+ T cells

Inclusion (n = 92)a

 PHA

6.95 (4.65–9.74)

6.37 (4.02–8.59)

 DBL-5

1.44 (0.49–2.32)

1.71 (0.67–2.46)

Delivery (n = 61)a

 PHA

4.28 (2.85–7.08)b

3.34 (2.01–5.49)b

 DBL-5

1.47 (0.65–2.02)

1.49 (0.98–2.27)

  1. Values are median frequencies (IQR)
  2. aNumbers are reduced due to insufficient quantities of PBMC to perform all assays
  3. bFrequencies significantly lower than corresponding frequencies at inclusion (p < 0.001 in both cases)
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Malaria Journal

ISSN: 1475-2875

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