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Table 5 Chloroquine pharmacokinetic parameters (n = 86)

From: Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment

 

Cmax

Tmax

AUC0–t

AUC0–inf

Vd

Cl

ng/mL

Days

Days (ng/mL)

Days (ng/mL)

mg/(ng/mL)

mg/days (ng/mL)

Mean

374.66

27.51

3700.43

3949.30

0.49

0.04

SD

129.57

2.09

1394.43

1431.95

0.34

0.02

CV

0.35

0.08

0.38

0.36

0.69

0.50

Minimum

122.10

14.0

690.60

826.84

0.16

0.02

Maximum

733.52

28.0

8045.24

9331.73

2.74

0.18