Fig. 5
From: Probucol dramatically enhances dihydroartemisinin effect in murine malaria
Effect of DHA on Plasmodium yoelii XL-17 infection in mice. Plasmodium yoelii XL17 (4 × 104 iRBC/head) were inoculated to C57BL/6 J males fed with regular commercial diet by intraperitoneal injection. The mice were treated with 7.5, 15 and 30 mg/kg of DHA by intraperitoneal injection on 3 to 5 days post infection once a day. Solvent was injected to mice as control. Survival rate (a) and parasitaemia (b) were monitored. Four mice were used for each group. The data are mean ± SD. DHA mice compared with mice injected with solvent: *p < 0.01. DHA 7.5, 15 mg/kg compared with 30 mg/kg DHA treated mice: # p < 0.05, ## p < 0.01