Cost effectiveness of intermittent screening followed by treatment versus intermittent preventive treatment during pregnancy in West Africa: analysis and modelling of results from a non-inferiority trial

Table 5 Threshold modelling for decreasing SP efficacy: Efficacy levels of IPTp-SP at which ISTp-AL becomes cost effective stratified by (1) two assumptions made on burden prevented by bed net use at a bed net coverage of 47.7 % and (2) willingness to pay threshold

	Full costs of RDT and AL		Costs of RDT and AL halved
	Bed nets bear 1/2 of extrapolated burden	Bed nets bear 2/3 of extrapolated burden	Bed nets bear 1/2 of extrapolated burden	Bed nets bear 2/3 of extrapolated burden
WTP 1 = US$ 861.33/DALY averted	Between 72 and 73 %	Between 69 and 70 %	Between 74 and 75 %	Between 71 and 72 %
WTP 2 = US$ 238.33/DALY averted	Between 63 and 64 %	Between 59 and 60 %	Between 68 and 69 %	Between 65 and 66 %
WTP3 = US$ 39.72/DALY averted	Between 19 and 20 %	Between 12 and 13 %	Between 41 and 42 %	Between 35 and 36 %

Results are shown for the full costs of RDT and AL as well as for the costs reduced by 50 %
The first column shows the three willingness to pay (WTP) thresholds
The first row indicates if the full costs for RDT and AL were used or if they were halved
The second row of the table show the two assumptions made regarding burden prevented by bed net use with bed nets bearing 1/2 and 2/3 respectively of the extrapolated burden of LBW, severe/moderate anemia and clinical malaria when IPTp-SP efficacy decreases Results shown here are based on a 47.7 % bed net coverage level