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Table 1 Cohort characteristics and malaria outcomes

From: Timing of in utero malaria exposure influences fetal CD4 T cell regulatory versus effector differentiation

Maternal characteristics

n (%)

Total enrollees

166

Maternal age (mean)

22.1

Previous pregnancies (%)

 0

56 (33.7)

 1

51 (30.7)

 2 or more

59 (35.5)

Randomized chemoprevention arm

 Dihydroartemisinin-piperaquine

86 (51.8)

 Sulfadoxine-pyrimethamine

80 (48.2)

Malaria outcomes

Positive n (%)

Assessments during pregnancy

 LAMPu at enrolment

89 (53.6)

 Any LAMP during monthly screening

81 (48.8)

Assessments at delivery

 Maternal peripheral blood

  Microscopy

4 (2.4)

  LAMP

20 (12.1)

Placental blood

 Microscopy

4 (2.4)

 LAMP

20 (12.1)

Cord blood

 Microscopy

0 (0)

 LAMP

3 (1.8)

Histopathology

63 (38.0)

 Parasites, pigment in monocytes ± fibrin

4 (2.4)

 Pigment only

59 (35.5)

Any malaria during pregnancy or delivery

131 (78.9)

Infant outcomes

n (%)

Preterm (<37 weeks)

9 (5.4)

Low birth weight (<2500 g)

9 (5.4)

  1. uLoop-mediated isothermal amplification