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Fig. 1 | Malaria Journal

Fig. 1

From: Exceptionally long-range haplotypes in Plasmodium falciparum chromosome 6 maintained in an endemic African population

Fig. 1

Microsatellite linkage disequilibrium and haplotypes across chromosome 6 of Plasmodium falciparum from the Gambia in 2008. a Mean pairwise linkage disequilibrium (r2) plotted against the physical position (base pairs on chromosome) of 775 polymorphic repeat loci across chromosome 6. Microsatellite genotypes were derived from short sequence reads of 54 P. falciparum isolates collected in 2008. The shaded box delineates the region of peak LD, representing the chromosome 6 selective sweep. b Zoom-in on 174 kb region of peak LD on panel ‘a’, showing the haplotypes from alleles (repeat-number) of 28 polymorphic microsatellite loci with at least three alleles. The first column in panel ‘b’ is the European Nucleotide Archive sample/data ID and the following columns are physical positions (bp) of chosen repeat loci on the chromosome. The numbers in cells are the repeat lengths and colour intensity for each cell in a column increases with increase in repeat lengths. Haplotypes defined by matching of loci alleles across the region are shown as grouped cells shaded with alternative intensities of grey and named arbitrarily from A to H

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