Size polymorphism and low sequence diversity in the locus encoding the Plasmodium vivax rhoptry neck protein 4 (PvRON4) in Colombian isolates

Table 2 Neutrality, linkage disequilibrium and recombination tests for the pvron4 gene in the Plasmodium vivax Colombian population

N	Gene	Tajima	Fu and Li		Fay and Wu’s H	Fu´s Fs	Z_nS	ZZ	RM
N	Gene	D	D*	F*	Fay and Wu’s H	Fu´s Fs	Z_nS	ZZ	RM
Colombian and reference isolates
80	2578	NP	NP	NP	NP	NP	0.154^τ	−0.002	0
Colombian isolates
73	2578	−0.037	−0.035	−0.020	−0.039	−0.028	0.163^τ	−0.002	0

No statistically significant values were found in neutrality tests
Z _nS average of R^2 for all comparison pairs, ZZ: Z _nS − Za difference, Rm minimum amount of recombination events, NP not performed, since not all sequences belonged to the same population
^τ p < 0.05

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