Fig. 1

Partial nucleotide sequences of the msp-3 gene of Plasmodium falciparum populations in Thailand. Only the nucleotide sequences encoding the AHRs of MSP-3, corresponding to nucleotide positions 232–570 after P. falciparum strain 3D7, are shown. H1 and H2 are derived from the 3D7 allele of msp-3, while the remaining 6 haplotypes (H3–5, H6A, H6B and H7) belong to the K1 allelic type. Two haplotypes, H6A and H6B, encode identical amino acid sequences (see Fig. 4). Grey and green labels indicate dimorphic and trimorphic nucleotides, respectively. Asterisks indicate dimorphic SNP defining the 3D7 and K1 alleles