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Table 2 Analysis of the molecular markers of P. falciparum linked to drug resistance

From: Failure of dihydroartemisinin-piperaquine treatment of uncomplicated Plasmodium falciparum malaria in a traveller coming from Ethiopia

  1. Specific point mutations in Pfcrt and Pfmdr1 gene are linked to quinoline-based antimalarial resistance; PfK13 is the molecular markers for artemisinin resistance; mutation I258M and Y268F/S in PfCytB gene are linked to atovaquone resistance; mutations in Pfdhfr/Pfdhps genes are responsible for P. falciparum resistance to antifolate-cycloguanil