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Fig. 1 | Malaria Journal

Fig. 1

From: Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

Fig. 1

Graphic representation of native Plasmodium falciparum CSP compared to RTS,S and the recombinant CSP. a Native P. falciparum circumsporozoite protein (CSP); b Recombinant CSP construct used in the RTS,S vaccine; c Recombinant full-length CSP construct used in present study. The full-length CSP sequence (amino acid 25–383) comprising the entire repeat sequence (38 NANP B cell epitopes) as well as T cell epitopes (CD4+ and CD8+) mapped in the N- and C-terminus, was genetically fused at the C-terminus to SpyCatcher

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Malaria Journal

ISSN: 1475-2875

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