Fig. 5

Anti-CSP IgG subclass profiling performed at a 14 days and b 42 days after first immunization. The proportion of anti-CSP IgG1, IgG2a, IgG2b and IgG3 in sera, obtained at day 14 and 42, relative to the total vaccine-induced IgG response in vaccinated mice (n = 6 for CSP-VLP vaccinated group and n = 5 for soluble CSP vaccine group). Mann–Whitney Rank Sum test was used for statistical comparisons