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Table 4 Studies documenting both community engagement and population coverage (n = 11, in chronological order)

From: Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review

Author, year and country Epidemiology (baseline parasitemia) Population coverage/% Type of study and the context Anti-malarial(s) Additional interventions
Archibald 1960, Nigeria [45] 48.7% 89.7 Non-RCT
Inhabitants of villages in Western Sokoto malaria control campaign
Chloroquine + pyrimethamine  
Clyde 1962, Tanzania [46] 59.8–64% 95 Before and after
Participants of all ages were recruited
Amodiaquine + primaquine IRS with DDT
Roberts 1964a, Kenya [40] 23% 95 Non-RCT
Participants of all ages were recruited and were from highlands in Kenya from 2 districts
Garfield 1983, Nicaragua [27] 0.42–0.83 cases/1000 population/month 70 Before and after (nationwide)
Medicine was administered to all persons aged >1 year over 3 days given once to the entire population
Chloroquine + primaquine  
Baukapur 1984, India [34] 0.18/1000 population/month 76 Before and after
All persons in 2 villages in Valsad District in Gujarat. Migratory population came from malarious areas during study period
Chloroquine NR
Pribadi 1986, Indonesia [31] 13.2% 93.7 Before and after
Mass chemoprophylaxis among all the individuals in Berakit village
Doi 1989b, Indonesia [44] 30% 100 Before and after
All aged participants were treated
SP + primaquine NR
Kaneko 2000, Vanuatu [35] 62% 88.3 Before and after
MDA was conducted with all individuals in Aneityum islands
Chloroquine + primaquine + SP  
Von Seidlein 2003, Gambia [42] 41.6% 85 RCT/Cluster RCT
Individuals older than 6 months and all non-pregnant women in 9 villages and placebo in other 9 villages
AS + SP  
Shekalaghe 2011, Tanzania [12] 0% by microscope and 2.6% by PCR 93 RCT/Cluster RCT
Individuals above 1 year were included. People who had received ACTs in 2 weeks prior to the study, pregnant women and people with anaemia received different drug regimen. Four each intervention and control randomly assigned
AS + SP + primaquine Vector control, larviciding
Lwin 2015, Thai–Myanmar border [25] 7.3% by microscopy and 18.4% by uPCR in one study village 40 Before and after
Study population consisted of all the villagers excluding children <14 years and pregnant women in Thai–Myanmar border
Dihydro-artemesinin + peperaquine NR