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Table 3 Main findings of studies that analysed pfcrt, dhfr and dhps genes

From: Malaria epidemiological research in the Republic of Congo

References Period of sample collection Year of publication pfcrt dhfr dhps dhfr and dhps (%)
76T (%) 51I 59R 108 N Triple 436A 437G 540E (%) Triple (%)
Nsimba et al. [23] 1999–2002 2005 97.1 82.4% 62.0% 86.6% 87.3% 17.5% 68.3% 0.0 73.0a/0.0b
Mayengue et al. [24] 2003 2005 98.0
Ndounga et al. [25] 2003–2004 2007 97.5 66.2 98.8 97.5 12.5 85.0 52.2a/6.2b
Tsumori et al. [11] 2005–2006 2011 88–97 50–68%
Koukouikila-Koussounda et al. [15] 2010 2012 92
Koukouikila-Koussounda et al. [36] 2012–2013 2015 88.0% 85.0% 79.1% 60.0% 67.1% 98.5% 55.2 >50 >50b/25.8c
  1. aQuadruple mutants
  2. bQuintuple mutants
  3. cSextuple mutants