Table 2 Clinical and parasitological characteristics at day 2

n (%)

8 (12.5%)

56 (87.5%)

Age (years)

Median (IQR)

7.5 (5–14.3)

12 (6–22)

0.236^a

 <8 years

n (%)

4 (50%)

19 (33.9%)

0.893^b

 8–15 years

n (%)

2 (25%)

15 (26.8%)

 >15 years

n (%)

2 (25%)

22 (39.3%)

Weight (kg)

Median (IQR)

26 (18–58.3)

39 (21–61)

0.551^a

P. falciparum density (parasites/µl)

Day 0

Median (IQR)

81,260 (35,110–133,200)

44,260 (17,720–87,300)

0.150^a

Day 2

Median (IQR)

293 (145–736)

0

Parasite decrease rate (%)

Median (IQR)

99.6 (98.9–99.8)

100

Symptoms n (%)

 Headache

0 (0%)

3 (5.3%)

1.000^c

 Vomiting

0 (0%)

1 (1.8%)

1.000^c

 Diarrhoea

0 (0%)

0 (0%)

1.000^c

 Diffuse pain

0 (0%)

0 (0%)

1.000^c

 Fever (≥38 °C)

0 (0%)

1 (1.8%)

1.000^c

Anti-malarial dose (mg/kg)

DHA

 Median (IQR)

2.4 (1.9–3.1)

2.4 (2.0–2.9)

0.570^a

 <25 kg

2.5 (2.4–3.4)

2.8 (2.4–3.4)

0.891^a

 ≥25 kg

2.3 (1.8–3.1)

2.1 (1.8–2.6)

0.425^a

PPQ

 Median (IQR)

19.4 (15.5–24.6)

18.8 (15.7–22.9)

0.570^a

 <25 kg

20.0 (18.8–03.5)

22.1 (18.8–27.5)

0.891^a

 ≥25 kg

18.3 (14.1–24.6)

17.1 (14.3–20.4)

0.425^a