Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification

Table 1 sWGA enrichment analysis

Mock and field samples were amplified by either WGA or sWGA before sequencing. Proportions of reads mapping to either human or P. falciparum genomes were used to determine the level of parasite DNA enrichment by sWGA treatment. 3D7 represent mock samples prepared by mixing P. falciparum and human genomic DNA in the ratio of 1:24 (4% parasite and 96% human). Field represent clinical genomic DNA samples extracted from dried blood spot filter papers

ISSN: 1475-2875