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Table 1 sWGA enrichment analysis

From: Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification

  Reads mapping to:
Sample P. falciparum (%) Human (%) Others (%) Fold enrichment
WGA_3D7_1 3.30 96.20 0.50 N/A
WGA_field_1 2.90 95.83 1.27 N/A
sWGA_3D7_1 79.74 3.33 16.94 19.93
sWGA_3D7_2 74.64 4.82 20.54 18.66
sWGA_Field_1 73.50 4.45 22.04 N/A
sWGA_Field_2 69.26 4.81 25.93 N/A
sWGA_Field_3 68.84 5.51 25.61 N/A
  1. Mock and field samples were amplified by either WGA or sWGA before sequencing. Proportions of reads mapping to either human or P. falciparum genomes were used to determine the level of parasite DNA enrichment by sWGA treatment. 3D7 represent mock samples prepared by mixing P. falciparum and human genomic DNA in the ratio of 1:24 (4% parasite and 96% human). Field represent clinical genomic DNA samples extracted from dried blood spot filter papers