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Table 1 Laboratory findings and progress

From: The dangers of accepting a single diagnosis: case report of concurrent Plasmodium knowlesi malaria and dengue infection

Investigations Normal range Day 1 (of admission) Day 2 Day 3 Day 4 Day 6 Day 9
Parasite counts (/µL)   520,000 460,000 320 120 Nil
Haemoglobin (g/dL) [13.5–17.5] 14.3 11.8 11.4 8.8 10.2 9.1
Platelet count (×109/L) [150–450] 33 17 20 78 175 277
Haematocrit (%) [42–54] 39.4 32.8 32.1 24.4 28.2 26.5
White blood cell count (×109/L) [4000–11,000] 6.91 6.87 9.21 10.97 17.39 9.25
Red blood cells (×1012/L) [4, 5] 4.55 3.78 3.72 2.95 3.44 3.15
Sodium (mmol/L) [135–150] 131 137 135 134 137 139
Potassium (mmol/L) [3.5–5.0] 4.5 5.4 5.3 4.7 4.1 3.9
Urea (mmol/L) [1.0–8.3] 7.9 18.2 29.7 26.4 29.8 19.6
Creatinine (µmol/L) [70–120] 116 275 405 425 512 346
Total bilirubin (mmol/L) [3–17] 46 44 39 35 25 17
Aspartate aminotransferase (U/L) [12–37] 80 104 92 78 37 31
Alanine aminotransferase (U/L) [20–65] 77 70 50 33 31 23
Alkaline phosphatase (U/L) [50–136] 151 135 119 97 110 95
Lactate dehydrogenase (U/L) [140–280] 994   2164   1680  
Creatine kinase (U/L) [<170] 177   221    
INR [0.8–1.2] 1.23 1.46 1.42 1.21 1.39 1.34
Prothrombin time (s) [11–14] 15.4 17.5 17.2 15.2 16.9 16.4
aPTT (s) [25–35] 44.3 55.9 51.0 54.8 59.9 47.6
NS1 antigen   Positive      
Dengue IgM   Positive      
CRP (mg/L) [<1] >200   >200   >200  
Random blood sugar (mmol/L) [6–10] 6.5 5.0 5.7 6.1 5.3 5.2
ABG   FMO2 5 L/min CPAP FiO2 60% BIPAP FiO2 60% BIPAP FiO2 60% CPAP FiO2 40% NPO2 3 L/min
pH [7.5–7.45] 7.36 7.247 7.28 7.35 7.43 7.43
PaO2 (mmHg) [>80] 77.4 100 133 142 89.1 111
PaCO2 (mmHg) [35–45] 25.6 30.4 25.7 28.8 30.9 38
HCO3 (mmol/L) [22–26] 21.2 16.1 14.3 17.7 22 25.5
Lactate (mmol/L) [<2] 1.8 3.5 2.8 1.2 0.8 0.6
  1. ABG arterial blood gas, aPTT activated partial thromboplastin time, BIPAP bilevel positive airway pressure, CPAP continuous positive airway pressure, CRP C-reactive protein, FMO2 face mask oxygen, IgM immunoglobulin M, INR international normalized ratio, NS1 nonstructural protein 1, PaCO 2 partial pressure of carbon dioxide, PaO 2 partial pressure of oxygen