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Table 1 Laboratory findings and progress

From: The dangers of accepting a single diagnosis: case report of concurrent Plasmodium knowlesi malaria and dengue infection

Investigations

Normal range

Day 1 (of admission)

Day 2

Day 3

Day 4

Day 6

Day 9

Parasite counts (/µL)

 

–

520,000

460,000

320

120

Nil

Haemoglobin (g/dL)

[13.5–17.5]

14.3

11.8

11.4

8.8

10.2

9.1

Platelet count (×109/L)

[150–450]

33

17

20

78

175

277

Haematocrit (%)

[42–54]

39.4

32.8

32.1

24.4

28.2

26.5

White blood cell count (×109/L)

[4000–11,000]

6.91

6.87

9.21

10.97

17.39

9.25

Red blood cells (×1012/L)

[4, 5]

4.55

3.78

3.72

2.95

3.44

3.15

Sodium (mmol/L)

[135–150]

131

137

135

134

137

139

Potassium (mmol/L)

[3.5–5.0]

4.5

5.4

5.3

4.7

4.1

3.9

Urea (mmol/L)

[1.0–8.3]

7.9

18.2

29.7

26.4

29.8

19.6

Creatinine (µmol/L)

[70–120]

116

275

405

425

512

346

Total bilirubin (mmol/L)

[3–17]

46

44

39

35

25

17

Aspartate aminotransferase (U/L)

[12–37]

80

104

92

78

37

31

Alanine aminotransferase (U/L)

[20–65]

77

70

50

33

31

23

Alkaline phosphatase (U/L)

[50–136]

151

135

119

97

110

95

Lactate dehydrogenase (U/L)

[140–280]

994

 

2164

 

1680

 

Creatine kinase (U/L)

[<170]

177

 

221

   

INR

[0.8–1.2]

1.23

1.46

1.42

1.21

1.39

1.34

Prothrombin time (s)

[11–14]

15.4

17.5

17.2

15.2

16.9

16.4

aPTT (s)

[25–35]

44.3

55.9

51.0

54.8

59.9

47.6

NS1 antigen

 

Positive

     

Dengue IgM

 

Positive

     

CRP (mg/L)

[<1]

>200

 

>200

 

>200

 

Random blood sugar (mmol/L)

[6–10]

6.5

5.0

5.7

6.1

5.3

5.2

ABG

 

FMO2 5 L/min

CPAP FiO2 60%

BIPAP FiO2 60%

BIPAP FiO2 60%

CPAP FiO2 40%

NPO2 3 L/min

pH

[7.5–7.45]

7.36

7.247

7.28

7.35

7.43

7.43

PaO2 (mmHg)

[>80]

77.4

100

133

142

89.1

111

PaCO2 (mmHg)

[35–45]

25.6

30.4

25.7

28.8

30.9

38

HCO3 (mmol/L)

[22–26]

21.2

16.1

14.3

17.7

22

25.5

Lactate (mmol/L)

[<2]

1.8

3.5

2.8

1.2

0.8

0.6

  1. ABG arterial blood gas, aPTT activated partial thromboplastin time, BIPAP bilevel positive airway pressure, CPAP continuous positive airway pressure, CRP C-reactive protein, FMO2 face mask oxygen, IgM immunoglobulin M, INR international normalized ratio, NS1 nonstructural protein 1, PaCO 2 partial pressure of carbon dioxide, PaO 2 partial pressure of oxygen