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Fig. 1 | Malaria Journal

Fig. 1

From: Genetic diversity of Plasmodium vivax metacaspase 1 and Plasmodium vivax multi-drug resistance 1 genes of field isolates from Mauritania, Sudan and Oman

Fig. 1

Alignment histidine and cysteine residues in the catalytic domain of metacaspases. The universally conserved histidine (His) and cysteine (Cys) residues are marked by a star in the catalytic site. In the PfMCA1 catalytic site, His–Cys are found at position 404 and 460. In the PvMCA1-cd, His–Cys, were identified at position 372 and 428, as well as in P. vivax from Mauritania, Brazil, India and North Korea. A second potential putative catalytic site His–Cys was also identified upstream of the catalytic domain at positions 282-305 in the five P. vivax sequences. Accessions of reference strains are PF13-0289 (ABC84559), PVX-114725 (EDL46606), PVMG-03834 (KMZ92479), PVBG-03488 (KMZ86023), PVIIG-01002 (KMZ79728), PVNG-00719 (KMZ98925)

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Malaria Journal

ISSN: 1475-2875

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