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Table 1 Mean per cent survival (individual values in brackets) of Cam3.IR539T isolate after 6 h exposure to a range of concentrations of DHA, OZ439 or OZ277 using the synchronization protocol from Xie et al. [53]

From: In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate

Compounds RSA values (% survival) at different concentrations
175 nM 350 nM 700 nM
DHA 46 (49, 43) 42 (45, 39) 37 (39, 35)
OZ277 4.0 (4.4, 3.6) 2.3 (1.9, 2.7) 1.4 (1.7, 1.1)
OZ439 <0.01 (<0.01, <0.01) <0.01 (<0.01, <0.01) <0.01 (<0.01, <0.01)
  1. Two biological replicates were performed per compound