Table 1 Mean per cent survival (individual values in brackets) of Cam3.IR539T isolate after 6 h exposure to a range of concentrations of DHA, OZ439 or OZ277 using the synchronization protocol from Xie et al. [53]
From: In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate
Compounds | RSA values (% survival) at different concentrations | ||
|---|---|---|---|
175 nM | 350 nM | 700 nM | |
DHA | 46 (49, 43) | 42 (45, 39) | 37 (39, 35) |
OZ277 | 4.0 (4.4, 3.6) | 2.3 (1.9, 2.7) | 1.4 (1.7, 1.1) |
OZ439 | <0.01 (<0.01, <0.01) | <0.01 (<0.01, <0.01) | <0.01 (<0.01, <0.01) |