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Fig. 1 | Malaria Journal

Fig. 1

From: Individuals living in a malaria-endemic area of Cameroon do not have an acquired antibody response to Plasmodium falciparum histidine-rich protein 2

Fig. 1

Titration of monoclonal antibodies to recombinant HRP2. Tenfold serial dilutions of murine ascites fluid containing monoclonal Ab to HRP2 (2G12, 87 and 1E1) and an irrelevant mAb (A2C7—negative control) were assayed on HRP2-coupled microspheres. Results are the mean ± SD for triplicate samples (technical replicates). The amount of HRP2-B coupled to the microspheres was fourfold lower than HRP2-A, explaining the difference in MFI values between the two datasets. The MFI observed with 1E1 (IgM) might be low, because the secondary reagent only detected IgM by light-chain reactivity

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