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Table 1 Antibody responses to MSP1-19 and AMA-1

From: Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda

Antigen Age group (years) Site No of participants Median age (IQR) Median OD (IQR) p value
Walukuba vs Kihihi Walukuba vs Nagongera Kihihi vs Nagongera
MSP1-19 1–4 Walukuba 12 3 (2–4) 0.71 (0.60–1.10) 0.08 0.041 0.44
Kihihi 18 3 (1–4) 0.90 (0.70–1.17)
Nagongera 24 1 (1–3) 1.00 (0.73–1.29)
5–15 Walukuba 16 12 (6–13) 0.80 (0.65–1.25) 0.5 0.4 0.8
Kihihi 76 12 (8–13) 0.89 (0.63–1.12)
Nagongera 74 11 (7–13) 0.87 (0.63–1.17)
>15 Walukuba 64 28 (20–40) 0.82 (0.61–1.1) 0.029 0.011 0.4
Kihihi 181 35 (25–48) 0.97 (0.70–1.27)
Nagongera 116 39 (25–55) 1.00 (0.67–1.30)
Total    581
AMA-1 1–4 Walukuba 18 2 (1–3) 0.86 (0.59–1.10) 0.95 0.18 0.19
Kihihi 21 3 (2–4) 0.79 (0.65–1.11)
Nagongera 63 3 (2–4) 0.92 (0.67–1.2)
5–15 Walukuba 76 9 (6–12) 0.92 (0.67–1.07) 0.005 0.0001 0.6
Kihihi 125 11 (8–13) 1.1 (0.80–1.15)
Nagongera 251 9 (7–12) 1.1 (0.85–1.2)
>15 Walukuba 89 27 (22–32) 0.72 (0.61–0.88) 0.0001 0.0007 0.62
Kihihi 197 34 (22–47) 0.85 (0.68–1.1)
Nagongera 189 34 (22–50) 0.87 (0.65–1.1)
Total    1029
  1. Statistically significant values (p < 0.05) are in italics
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