Fig. 3
From: Anti-malarial effect of novel chloroquine derivatives as agents for the treatment of malaria
Effect of SKM13 against chloroquine-resistant strain P. berghei in a 4-day suppression test. Plasmodium berghei (NAT) parasites (107/mouse) were injected via the i.p. route in mice (n = 7) and after 1 day, drugs were administered in the mouse vein for four consecutive days. After drug treatment, parasitaemia and weight were measured every day (a normal group, b P. berghei-infected group, c SKM13-treated group, d CQ-treated group, e atovaquone-treated group; red square, parasitaemia; white circle, body weight) (**P < 0.01, ***P < 0.001). The values shown are the mean ± SD. The survival rate (% of control) is shown in (f)