Fig. 1From: MinorityReport, software for generalized analysis of causal genetic variantsExperimental scheme. MinorityReport deciphers nonsynonymous mutations, including those that enable drug resistance in pathogens. A susceptible pathogen strain (green) is cultivated in sub-LD100 concentrations of a drug until a resistant strain (blue) emerges. The genomes are sequenced, aligned to a reference genome, and MinorityReport outputs the causative mutation, which is often also the drug targetBack to article page