Skip to main content

Table 2 Test of neutrality for Plasmodium falciparum surf 4.1 for the western Kenyan isolates (n = 24)

From: Selections, frameshift mutations, and copy number variation detected on the surf 4.1 gene in the western Kenyan Plasmodium falciparum population

Region Nucleotide position Number of sites (base) η S Two variants More than two variants π θ Tajima’s D Fu and Li’s
Singleton Not singleton D* F*
Extracellular 4–2289 2286 439 410 115 266 29 0.046 0.048 −0.19 −0.29 −0.30
Nter 4–150 147 2 2 1 1 0 0.002 0.004 −1.20 −0.66 −0.93
CRD 151–585 435 11 10 3 6 1 0.007 0.006 0.39 −0.61 −0.36
Var1 586–1506 918 109 107 44 61 2 0.022 0.031 −1.17 −0.93 −1.18
Var2 1507–2289 783 317 291 67 198 26 0.104 0.100 0.17 −0.02 0.05
  1. Sequence number is after 3D7 line sequence
  2. Extracellular, extracellular region; Nter, N-terminal segment; CRD, cysteine-rich domain; Var1, variable region 1; Var2, variable region 2; sites, nucleotide sites analyzed; η, the total number of mutations; S, number of segregating sites; π, observed nucleotide diversity; θ, the expected nucleotide diversity under neutrality derived from S