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Table 3 Relationship between haemoglobin types and haematological indices in children with malaria

From: Assessing the impact of differences in malaria transmission intensity on clinical and haematological indices in children with malaria

Haematological indices

Haemoglobin type

P value

AA

(N = 346)

AS

(N = 46)

AC

(N = 37)

Median (IQR)

Median (IQR)

Median (IQR)

Erythrocyte indices

 Haemoglobin (g/dL)a

10.3 (9.0–11.4)

10.80 (9.4–11.65)

10.30 (8.57–11.55)

0.219#

 RBC (103/mm3)

4.1 (3.7–4.5)

4.3 (3.9–4.6)

4.2 (3.6–4.8)

0.187

 MCV (µm3)

77.0 (73.0–80.0)

74.5 (71.8–77.9)

73.5 (68.7–79.0)

0.007

 MCH (pg.)

25.6 (23.8–26.9)

24.5 (23.7–26.6)

24.7 (22.7–25.7)

0.008

 MCHC (g/dL)

33.3 (32.2–34.4)

33.4 (32.2–34.4)

32.8 (32.1–34.3)

0.743

 RDW (%)

15.4 (14.3–16.7)

16.2 (15.0–17.4)

15.6 (14.8–17.4)

0.002

Leucocyte indices

 WBC (103/mm3)

8.2 (6.2–10.5)

8.9 (6.1–11.0)

9.0 (6.9–13.0)

0.058

 LYM (%)

27.3 (17.1–40.5)

26.3 (17.4–41.3)

27.0 (15.9–44.0)

0.373

 MON (%)

6.3 (4.8–8.6)

6.4 (5.1–8.5)

6.4 (5.1–8.3)

0.253

 GRA (%)

64.5 (49.5–76.4)

63.7 (51.7–76.9)

62.7 (44.6–74.8)

0.226

Platelet indices

 PLT (103/mm3)

141 (92.0–211.0)

166.5 (106.0–231.3)

137.0 (79.0–234.0)

0.044

 MPV (µm3)

7.8 (7.3–8.5)

7.6 (6.9–8.1)

7.5 (7.1–8.5)

0.043

 PDW (%)

14.6 (12.4–16.7)

14.4 (11.5–16.3)

14.4 (11.9–18.7)

0.555

  1. Data are presented as medians (first quartile-third quartile)
  2. # P value obtained from ANOVA
  3. aSample sizes for haemoglobin levels were AA = 431, AS = 49 and AC = 49