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Table 3 Allele frequencies at resistance associated pfdhps codons 436, 437, 514, 540, 581 and 613

From: Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976–78

Village S436 A437 I514 K540 A581 A613 613 S
Chlorproguanil 40/40 40/40 32/32 32/32 32/32 29/32 (91%) 3 (9%)
Pyrimethamine 38/38 38/38 38/38 38/38 38/38 38/38 0 a
Chloroquine 30/30 30/30 26/26 26/26 26/26 19/26 (73%) 7(27%)
Vitamin B 40/40 40/40 40/40 40/40 40/40 35/39 (90%) 4 (10%)
  1. Resistance associated alleles are shown in italics
  2. aThe frequency of samples with the resistance associated pfdhps 613S was lower in the pyrimethamine treated village compared to pooled frequencies from the other villages (P < 0.01) and the village using CQ (P = 0.001)