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Table 2 Genotype and allele frequencies for the single nucleotide polymorphisms rs5743899 and, rs3750920 in patients with and, without P. vivax malaria

From: TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon

Polymorphism, genotypes and, alleles P. vivax malaria patients Controls
n = 301 (%) n = 255 (%)
TOLLIP rs5743899
 GG 32 (11) 24 (10)
 GA 124 (41) 108 (42)
 AA 145 (48) 123 (48)
 G 188 (31) 156 (31)
 A 414 (69) 354 (69)
Polymorphism, genotypes and, alleles P. vivax malaria patients Controls
n = 319 (%) n = 263 (%)
TOLLIP rs3750920
 CC 66 (21) 68 (26)
 CT 134 (42) 132 (50)
 TT 119 (37) 63 (24)
 C 133 (42) 134 (51)
 T 186 (58) 129 (49)
Polymorphism, genotypes and, alleles P. vivax malaria patients Controls
p value OR [95% CI]
Genotypes and alleles comparisons
TOLLIP rs3750920
 CC vs. TT 0.004 1.95 [1.23–3.07]
 CC + CT vs. TT 0.0005 0.52 [0.37–0.76]
 TT vs. CT 0.002 0.53 [0.36–0.79]
 T vs. C 0.002 0.69 [0.55–0.87]
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