Table 2 Genotype and allele frequencies for the single nucleotide polymorphisms rs5743899 and, rs3750920 in patients with and, without P. vivax malaria
From: TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon
Polymorphism, genotypes and, alleles | P. vivax malaria patients | Controls |
|---|---|---|
n = 301 (%) | n = 255 (%) | |
TOLLIP rs5743899 | ||
 GG | 32 (11) | 24 (10) |
 GA | 124 (41) | 108 (42) |
 AA | 145 (48) | 123 (48) |
 G | 188 (31) | 156 (31) |
 A | 414 (69) | 354 (69) |
Polymorphism, genotypes and, alleles | P. vivax malaria patients | Controls |
|---|---|---|
n = 319 (%) | n = 263 (%) | |
TOLLIP rs3750920 | ||
 CC | 66 (21) | 68 (26) |
 CT | 134 (42) | 132 (50) |
 TT | 119 (37) | 63 (24) |
 C | 133 (42) | 134 (51) |
 T | 186 (58) | 129 (49) |
Polymorphism, genotypes and, alleles | P. vivax malaria patients | Controls |
|---|---|---|
p value | OR [95% CI] | |
Genotypes and alleles comparisons TOLLIP rs3750920 | ||
 CC vs. TT | 0.004 | 1.95 [1.23–3.07] |
 CC + CT vs. TT | 0.0005 | 0.52 [0.37–0.76] |
 TT vs. CT | 0.002 | 0.53 [0.36–0.79] |
 T vs. C | 0.002 | 0.69 [0.55–0.87] |