Fig. 6

Effect of PQ-TZ 4m on infected hepatocytes in vitro. Number (a) and size (b) of the exoerythrocytic forms of P. berghei (EEF) in cultures of mouse hepatocytes (cell line Hepa1-6), in the presence of compound PQ-TZ 4m at 0.1, 1 and 10 µM concentrations. Representative EEFs in control (c) or 10 µM PQ-TZ 4m-treated Hepa1-6 cells (d). The same image is shown for each in phase, stained with DAPI, and, stained with mAb 3D11 against the developing EEF. **p < 0.05 by Mann–Whitney test. Need size bars