Table 3 Prevalence of the individual single nucleotide polymorphisms (SNPs) in all study sites
From: Clinical and molecular surveillance of drug resistant vivax malaria in Myanmar (2009–2016)
Target genes | Kawthaung (n = 60) | Shwegyin (n = 88) | Buthidaung (n = 60) | All site (n = 208) | P value |
|---|---|---|---|---|---|
pvcrt-O | |||||
‘AAG’ insert | 40 (66.7) | 64 (72.7) | 29 (48.3) | 133 (63.9) | 0.009 |
pvmdr1 | |||||
T958M | 60 (100.0) | 88 (100.0) | 60 (100.0) | 208 (100.0) | NR |
Y976F | 16 (26.7) | 15 (17.0) | 1 (1.7) | 32 (15.4) | 0.001 |
F1076L | 25 (41.7) | 43 (48.9) | 38 (63.3) | 106 (51.0) | 0.067 |
pvdhps | |||||
S382A | 32 (53.3) | 24 (27.3) | 5 (8.3) | 61 (29.3) | 0.000 |
A383G | 60 (100.0) | 87 (98.9) | 30 (50.0) | 177 (85.1) | 0.000 |
K512M | 22 (36.7) | 10 (11.4) | 7 (11.7) | 39 (18.8) | 0.000 |
A553G | 55 (91.7) | 71 (80.7) | 28 (46.7) | 154 (74.0) | 0.000 |
pvdhfr | |||||
F57L/I | 46 (76.7) | 73 (83.0) | 35 (58.3) | 154 (74.0) | 0.001 |
S58R | 59 (98.3) | 88 (100.0) | 48 (80.0) | 195 (93.8) | 0.000 |
T61M | 45 (75.0) | 71 (80.7) | 32 (53.3) | 148 (71.2) | 0.001 |
S117T/N | 58 (96.7) | 86 (97.7) | 52 (86.6) | 196 (94.2) | 0.003 |