Table 4 Prevalence of k13 mutations by study
k13 genotype | Muse 2011–12 | Tamu 2012 | Tabeikkyin 2014 | Tamu 2014 | Grand total n (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
AL n | AS + MQ n | Total n (%) | AL n | AS + MQ n | Total n (%) | AL n | DP n | Total n (%) | DP n (%) | ||
F446I | 1 | 8 | 9 (12.7) | 19 | 6 | 25 (25.8) | 10 | 6 | 16 (25.4) | 14 (24.6) | 64 (22.2) |
N458Y | 0 | 0 | 0 (0) | 0 | 0 | 0 (0) | 3 | 4 | 7 (11.1) | 0 (0) | 7 (2.4) |
S459L | 0 | 0 | 0 (0) | 0 | 0 | 0 (0) | 0 | 1 | 1 (1.6) | 0 (0) | 1 (0.3) |
P553L | 0 | 0 | 0 (0) | 0 | 1 | 1 (1) | 1 | 0 | 1 (1.6) | 0 (0) | 2 (0.7) |
R561H | 1 | 1 | 2 (2.8) | 0 | 0 | 0 (0) | 3 | 3 | 6 (9.5) | 7 (12.3) | 15 (5.2) |
P574L | 5 | 0 | 5 (7) | 0 | 1 | 1 (1) | 0 | 0 | 0 (0) | 0 (0) | 6 (2.1) |
A676D | 0 | 0 | 0 (0) | 0 | 1 | 1 (1) | 0 | 0 | 0 (0) | 0 (0) | 1 (0.3) |
P701R | 1 | 0 | 1 (1.4) | 0 | 0 | 0 (0) | 0 | 0 | 0 (0) | 0 (0) | 1 (0.3) |
Total k13 mutations | 8 | 9 | 17 (23.9) | 19 | 9 | 28 (28.9) | 17 | 14 | 31 (49.2) | 21 (36.8) | 97 (33.7) |
Wild type | 38 | 16 | 54 (76.1) | 41 | 28 | 69 (71.1) | 16 | 16 | 32 (50.8) | 36 (63.2) | 191 (66.3) |
Total cases genotyped | 46 | 25 | 71 | 60 | 37 | 97 | 33 | 30 | 63 | 57 | 288 |