Table 3 Analytical sensitivity of selected pLDH-based RDTs
From: Analytical sensitivity of current best-in-class malaria rapid diagnostic tests
Sample type | Sample | Pv-pLDH | Pvom-pLDH | Pf-pLDH | Pan-pLDH | |||||
|---|---|---|---|---|---|---|---|---|---|---|
RDT 6 (ng/mL) | RDT 7 (ng/mL) | RDT 8 (ng/mL) | RDT 9 (ng/mL) | RDT 10 (ng/mL) | RDT 11 (ng/mL) | RDT 10 (ng/mL) | RDT 12 (ng/mL) | RDT 13 (ng/mL) | ||
P. vivax isolate | Pv1 | 25 | 25 | 25 | 12.5 | – | – | 500 | 50 | 5 |
Pv2 | 25 | 25 | 25 | 5 | – | – | 1000 | 25 | 5 | |
Pv3 | 12.5 | 25 | 25 | 5 | – | – | 250 | 25 | 5 | |
Pv4 | 25 | 25 | 25 | 10 | – | – | 500 | 25 | 10 | |
Pv5 | 25 | 50 | 25 | 5 | – | – | 1000 | 25 | 10 | |
P. vivax rec. protein | Pv-pLDH EC | 10 | 25 | 12.5 | 2.5 | 500 a | – | 500 | 25 | 5 |
Pv-pLDH EUK | 25 | 25 | 25 | 20 | – | – | 1000 | 50 | 12.5 | |
P. falciparum culture | FCQ79 | – | – | – | – | 2.5 | 0.5 | 2.5 | 50 | 5 |
W2 | – | – | – | – | 5 | 1 | 5 | 50 | 10 | |
PH1 | – | – | – | – | 2.5 | 1 | 2.5 | 25 | 5 | |
P. falciparum rec. protein | Pf-pLDH EC | 5000 a | – | – | 5000 a | 25 | 10 | 25 | 25 | 10 |
Pf-pLDH EUK | – | – | – | – | 100 | 10 | 50 | 25 | 20 | |