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Table 3 Analytical sensitivity of selected pLDH-based RDTs

From: Analytical sensitivity of current best-in-class malaria rapid diagnostic tests

Sample type Sample Pv-pLDH Pvom-pLDH Pf-pLDH Pan-pLDH
RDT 6 (ng/mL) RDT 7 (ng/mL) RDT 8 (ng/mL) RDT 9 (ng/mL) RDT 10 (ng/mL) RDT 11 (ng/mL) RDT 10 (ng/mL) RDT 12 (ng/mL) RDT 13 (ng/mL)
P. vivax isolate Pv1 25 25 25 12.5 500 50 5
Pv2 25 25 25 5 1000 25 5
Pv3 12.5 25 25 5 250 25 5
Pv4 25 25 25 10 500 25 10
Pv5 25 50 25 5 1000 25 10
P. vivax rec. protein Pv-pLDH EC 10 25 12.5 2.5 500 a 500 25 5
Pv-pLDH EUK 25 25 25 20 1000 50 12.5
P. falciparum culture FCQ79 2.5 0.5 2.5 50 5
W2 5 1 5 50 10
PH1 2.5 1 2.5 25 5
P. falciparum rec. protein Pf-pLDH EC 5000 a 5000 a 25 10 25 25 10
Pf-pLDH EUK 100 10 50 25 20
  1. A dash indicates a combination for which no reactivity was seen up to the highest concentration tested
  2. aFalse positive results