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Table 2 Summary of multiple linear regression analysis for predictors of cytokine levels

From: Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity

  TNF-α IL-12 IFN-γ IL-1β IL-2 IL-6 IL-8 IL-4 IL-10 IL-13 IL-7 GM-CSF
Variables (df, error) F P F P F P F P F P F P F P F P F P F P F P F P
Age (1,171) 0.48 0.490 2.02 0.15 0.37 0.54 1.41 0.23 1.74 0.18 1.41 0.236 0.76 0.38 2.00 0.159 0.00 0.954 2.98 0.086 0.23 0.635 2.35 0.127
Parasitemia (1,171) 0.80 0.37 0.44 0.510 0.25 0.61 0.02 0.88 1.47 0.22 0.02 0.880 0.29 0.590 0.29 0.59 8.99 0.003 #* 1.79 0.183 0.24 0.625 1.27 0.261
Sex (1,171) 0.82 0.366 0.39 0.53 0.01 0.914 0.10 0.750 3.18 0.076 0.10 0.750 0.01 0.937 0.08 0.782 0.04 0.837 0.18 0.67 0.12 0.729 6.64 0.011#
Transmission Intensity (2,171) 2.43 0.091 6.51 0.002#* 6.38 0.001#* 7.36 0.001#* 9.26 <0.0001#* 7.36 0.001#* 9.78 <0.0001#* 8.09 <0.0001#* 13.26 <0.0001#* 5.04 0.007# 10.02 <0.0001#* 1.74 0.178
  1. Table summarizing the multiple linear regression analyses. Cytokine levels were the outcome variables, while age, parasitemia, sex and transmission intensity (sites) were the predictor variables. Transmission intensity was the major significant predictor of cytokine levels
  2. F = F-statistic
  3. df = Degree of freedom
  4. Error = Residual degrees of freedom
  5. #Statistically significant predictor
  6. *Significant after Bonferroni’s P value adjustment