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Table 4 Prevalence of single, double, triple, quadruple and quintuple mutation in Tanzania and Senegal

From: High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations

 

Single mutation (%)

Double mutation (%)

Triple mutation (%)

Quadruple mutation (%)

Quintuple mutation (%)

Senegal

20

22

44

52

0

Tanzania

2

2

48

58

0

p value

0.01

0.005

0.84

0.7

0

  1. Mutant alleles from dhfr, dhps genes were combined to make the single mutation (S108N), double mutation (dhfr C59R/S108N), triple mutation (dhfr N51I/C59R/S108 N), quadruple mutation (dhfr N51I/C59R/S108N dhps A437G) and quintuple mutation (N51I/C59R/S108N dhfr and A437G/K540E dhps)
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Malaria Journal

ISSN: 1475-2875

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