|
Reference
|
Pos
|
Neg
|
Pos
|
Neg
|
Pos
|
Neg
|
Total
|
|---|
|
CLIP-PCR
|
nD-PCR
|
nRT-PCR
|
|---|
|
LM
|
|
Pos
|
6
|
6
|
11
|
1
|
12
|
0
|
12
|
|
Neg
|
13
|
980
|
13
|
980
|
175
|
818
|
993
|
|
Total
|
19
|
986
|
24
|
981
|
187
|
818
|
1005
|
|
Sensitivity (95% CI)
|
50.0% (46.9–53.0%)
|
91.7% (90–93.4%)
|
100% (100–100%)
| |
|
Specificity (95% CI)
|
98.7% (92.3–100%)
|
98.7% (92.3–100%)
|
82.4% (60.8–100%)
|
|
Reference
|
LM
|
nD-PCR
|
nRT-PCR
|
Total
|
|---|
|
CLIP-PCR
|
|
Pos
|
6
|
13
|
12
|
7
|
19
|
0
|
19
|
|
Neg
|
6
|
980
|
12
|
974
|
168
|
818
|
986
|
|
Total
|
12
|
993
|
24
|
981
|
187
|
818
|
1005
|
|
Sensitivity (95% CI)
|
31.6% (28.7–34.5%)
|
63.2% (60.1–66.2%)
|
100% (100–100%)
| |
|
Specificity (95% CI)
|
99.4% (95.9–100%)
|
98.8% (93.9–100%)
|
83.0% (66.0–99.9%)
| |
|
Reference
|
CLIP-PCR
|
LM
|
nRT-PCR
|
Total
|
|---|
|
nD-PCR
|
|
Pos
|
12
|
12
|
11
|
13
|
24
|
0
|
24
|
|
Neg
|
7
|
974
|
1
|
980
|
163
|
818
|
981
|
|
Total
|
19
|
986
|
12
|
993
|
187
|
818
|
1005
|
|
Sensitivity (95% CI)
|
50.0% (46.9–53.1%)
|
45.8% (42.7–49.0%)
|
100% (100–100%)
| |
|
Specificity (95% CI)
|
99.3% (95.9–100%)
|
99.9% (98.6–100%)
|
83.38% (68.5–98.3%)
| |
|
Reference
|
CLIP-PCR
|
nD-PCR
|
LM
|
Total
|
|---|
|
nRT-PCR
|
|
Pos
|
19
|
168
|
24
|
163
|
12
|
175
|
187
|
|
Neg
|
0
|
818
|
0
|
818
|
0
|
818
|
818
|
|
Total
|
19
|
986
|
24
|
981
|
12
|
993
|
1005
|
|
Sensitivity (95% CI)
|
10.2% (8.1–12.2%)
|
12.8% (10.5–15.1%)
|
6.4% (4.8–8.1%)
| |
|
Specificity (95% CI)
|
100% (100–100%)
|
100% (100–100%)
|
100% (100–100%)
| |
