Table 4 Prevalence of Pfatp6 and Pfk13 gene polymorphisms
Locus | Mutation | Cohort 2010 (%) | Cohort 2015 (%) |
|---|---|---|---|
Pfatp6 | H243Y | 2/8 (25) | 0/16 (0) |
I291V | 0/8 (0) | 1/16 (6) | |
L402V | 1/8 (12) | 2/16 (12) | |
E431K | 1/8 (12) | 2/16 (12) | |
N569K | 5/8 (63) | 2/16 (12) | |
A630S | 3/8 (38) | 0/16 (0) | |
G632E | 0/8 (0) | 1/16 (6) | |
G639D | 0/8 (0) | 1/16 (6) | |
F646F | 1/8 (12) | 0/16 (0) | |
H747Y | 0/8 (0) | 1/16 (6) | |
Pfk13 | D464N | 1/41 (2) | 0/25 (0) |
S466I | 0/41 (0) | 1/25 (4) | |
Q467H | 0/41 (0) | 1/25 (4) | |
N489N | 0/41 (0) | 1/25 (4) | |
G496G | 0/41 (0) | 1/25 (4) | |
R539R | 1/41 (2) | 0/25 (0) | |
S549P | 1/41 (2) | 0/25 (0) | |
I552M | 0/41 (0) | 1/25 (4) | |
L598L | 1/41 (2) | 0/25 (0) | |
E602E | 1/41 (2) | 0/25 (0) | |
N609N | 0/41 (0) | 1/25 (4) | |
F628L | 0/41 (0) | 1/25 (4) | |
K669K | 1/41 (2) | 0/25 (0) |